Cephaloridine in gonorrhoea in females.

Material and Management Cephaloridine ("Ceporin") was used to treat 255 attacks of uncomplicated gonorrhoea (other than gonococcal proctitis) in 234 women. Of these 234 patients, 182 were born in the United Kingdom, 26 were from Southern Ireland, 26 from the West Indies, and the remaining three from India. 34 per cent. of the patients were aged between 13 and 19 years, 31 per cent. between 20 and 24 years, and 34 per cent. over 24 years. The diagnosis of gonorrhoea was based on the recognition of diplococci morphologically identical to gonococci in films stained by Gram's or Sandiford's methods, or on the presence of gonococci in chocolate agar cultures. Specimens for films and cultures were taken from the urethra, the vagina, and the cervix, and at times from the rectum. Treatment consisted of either 2 g. cephaloridine given as a single injection or of one injection of 1 g. repeated the following day. These treatments were given alternately except on Saturdays when all patients were given 2g. cephaloridine. Table I shows the number of patients receiving each treatment and their age distribution.